QD Clinic

Cinderella InjectionGangnam, Seoul

The Cinderella injection is a Korean nickname for thioctic acid (alpha-lipoic acid) injection — the MFDS refers to it as “thioctic acid injection (a.k.a. Cinderella injection)”. Its approved indications in Korea depend on the formulation, and none of them include weight loss or relief of fatigue. QD Clinic first checks whether you take blood-sugar medication and how fast it can be given. At QD Clinic in Gangnam, Seoul, South Korea, consultation helps determine which options suit your concerns.

Illustrative image for understanding Cinderella Injection Gangnam, Seoul

Who it’s for

  • You want to confirm what the Cinderella injection really contains
  • You take blood-sugar medication and want to know whether it is safe for you
  • Your face has flushed or you have felt short of breath during an injection before

If weight management is your goal, we discuss evidence-based approaches such as diet, activity and medication rather than this injection.

How it works

Thioctic acid 600mg injection is approved for “relief of diabetic polyneuropathy”. In the MFDS drug database (nedrug), thioctic acid 600mg (trometamol salt) injection is approved for “relief of diabetic polyneuropathy”. Low-concentration (5mg/mL) thioctic acid injections are approved for uses such as “supplementation when the need for thioctic acid increases (during strenuous physical labor)”, with a note that they should not be continued if there is no effect after about a month. There are no cosmetic or weight-related indications.

THE MECHANISM, STEP BY STEP

  • 01Ingredient

    The active ingredient is thioctic acid (alpha-lipoic acid). Unlike supplements of the same name, the injection is a prescription-only medicine.

  • 02Approved use by formulation

    The 600mg trometamol salt product is approved for relief of diabetic polyneuropathy; the 5mg/mL product has different approvals, such as supplementation when the need increases and some types of hearing loss.

  • 03Infusion speed

    The 600mg product is diluted in 100–250mL of normal saline and given over at least 12 minutes, at no more than 50mg of thioctic acid per minute.

  • 04Protection from light

    Because the ingredient is unstable in light, ampoules are taken out just before use and the diluted infusion is covered with aluminum foil or similar.

Treatment areas

Discuss at consultation
We first ask whether you use insulin or other glucose-lowering medicines for diabetes. The product information lists rare hypoglycemia.
Medical assessment
Weight loss and fatigue relief are not approved indications. Tell us exactly what you hope for, and we will explain whether there is evidence for it.
Before treatment
The ingredient is sensitive to light, so the product information says the diluted infusion must be shielded from light.

What the procedure is like

  1. 1Medical history — diabetes and blood-sugar medicines, history of hypersensitivity
  2. 2Dilution and light-shielded preparation
  3. 3Drip infusion at the set speed
  4. 4Check for dizziness or low blood sugar after the infusion

The approved method for the 600mg product is infusion over at least 12 minutes. The actual time depends on the dilution volume.

Recovery & aftercare

  • If you feel dizzy after the infusion, stay seated for a while rather than standing up straight away.
  • If you take diabetes medication, don’t skip meals after you get home.
  • Bruising at the needle site usually fades within a few days.

What to expect over time

A general guide to how the days and months after treatment usually unfold. Results vary by individual.

  1. During infusion Reactions to fast infusion

    The product information says a rush of blood to the head and breathing difficulty can often occur after rapid infusion and fade with time. Tell us straight away if you feel unwell.

  2. Right after Signs of low blood sugar

    Very rarely, blood sugar may drop, causing dizziness, sweating, headache or visual disturbance.

  3. After you get home Hypersensitivity

    If you develop a skin rash, hives or itching, let us know before your next session.

Sessions & results

The label for the low-concentration product says “if no effect appears even after about one month of use, do not continue”, so we decide afresh each time whether to continue.

How it compares

Two injections often mentioned alongside the Cinderella injection, compared by ingredient.

ComparisonCinderella InjectionGarlic InjectionGlutathione Injection (White Jade)
Active ingredientThioctic acidFursultiamine (a vitamin B1 derivative)Reduced glutathione
Main approved indicationsRelief of diabetic polyneuropathyPrevention and treatment of vitamin B1 deficiency, etc.Drug poisoning; improving liver function in chronic liver disease
Infusion precautions in the labelNo more than 50mg/min, over at least 12 minutesAs slowly as possible, as it can cause vein painVials used immediately after dissolving

All based on Korean-approved products with the same ingredient. None of the three is approved for weight loss or fatigue relief.

Safety & considerations

Contraindications in the label

  • Hypersensitivity to thioctic acid or any component
  • Children and adolescents (limited clinical experience)

Adverse reactions in the label

  • Very rarely, hypersensitivity reactions up to shock; skin rash, hives, itching
  • Occasionally nausea, vomiting, changes in taste
  • Rush of blood to the head and breathing difficulty after rapid infusion
  • Very rarely, low blood sugar (dizziness, sweating, headache, visual disturbance)

The Cinderella injection is not a medicine approved for weight loss or fatigue relief. If you are being treated for diabetes, you must tell us beforehand. Individual responses vary.

Your care at QD Clinic

  • Blood-sugar check

    We check for diabetes, use of insulin or glucose-lowering medicines, and when you last ate.

  • Expectations vs approved use

    We set what you hope for side by side with thioctic acid’s approved indications.

  • Infusion at the set speed

    We stay within the approved infusion speed and watch for headache, dizziness or sweating during the infusion.

Frequently asked questions

  • Thioctic acid, commonly known as alpha-lipoic acid. When the MFDS revised its safe-use manual for these medicines in 2018, it named it “thioctic acid injection (a.k.a. Cinderella injection)”. Unlike dietary supplements with the same name, the injection is a prescription-only medicine.

  • Weight loss is not an approved indication in Korea. The 600mg product is approved for relief of diabetic polyneuropathy. If weight is your concern, we can discuss other evidence-based options with you.

  • You must tell us before you have it. The product information says that because glucose utilization improves, blood sugar can very rarely fall, and when it overlaps with insulin or glucose-lowering medicines the risk of hypoglycemia needs to be assessed separately. After the infusion, dizziness, sweating, headache or vision problems can be signs of low blood sugar, so tell us straight away. Don’t skip meals after you get home, either.

  • That is the approved method. The 600mg product is given over at least 12 minutes at no more than 50mg per minute. The label notes that giving it faster can cause a rush of blood to the head or breathing difficulty.

  • Because thioctic acid is unstable in light. The product information says the diluted infusion should be shielded from light with aluminum foil or similar, and that the shielded solution stays stable for about 6 hours. For the same reason, the ampoule is taken out only just before use.

For international patients

Consultation in English / 中文 / 日本語 · WhatsApp · WeChat · KakaoTalk · a 4-minute walk from Sinnonhyeon / Nonhyeon Station (hours in KST).

How many days should I stay?

Surgery and course-based treatments need a check-up. We tell you before you book whether that means staying longer or coming back another time.

For International Patients