A Guide to Korean Skin Boosters: Rejuran Healer, Rejuran HB, Rejuran i, Rejuran S

If you had to name the treatment that pioneered the Korean skin booster market and continues to enjoy overwhelming popularity to this day, it would undoubtedly be 'Rejuran.' While it began as a single product, Rejuran has since developed a specialized lineup tailored to patients' diverse skin concerns and the unique characteristics of different treatment areas.

Going beyond simple full-face injections, customized treatments are now available to perfectly meet specific goals—whether that means minimizing pain or targeting fine lines around the eyes and indented scars. At Gangnam Dermatology QD Clinic,here is a clear breakdown of the features, benefits, and precautions of the four core Rejuran lineups (Healer, HB Plus, i, and S).

The Core of Rejuran: What is PN (Polynucleotide)?

To understand the Rejuran lineup, you need to know its core ingredient, PN (Polynucleotide). While it is similar to PDRN, which is commonly used in skin boosters, PN is a high-molecular-weight polymer created by linking the substances extracted from salmon DNA into longer and denser chains.

Due to its large particle size and high viscosity, it stays in the skin longer, powerfully inducing the healing of the dermal layer and collagen regeneration. The core principle of Rejuran treatments is to build a 'framework for regeneration' so that the skin can heal and become healthy on its own.

1. Rejuran Healer: The Original Regeneration Booster

Treatment Features This is the 'original' treatment that forms the foundation of the Rejuran lineup. Consisting solely of pure PN, it is densely injected into the dermal layer across the entire face to improve the fundamental environment of the skin. At QD Dermatology Clinic, Rejuran Healer is often recommended for patients who want overall skin quality improvement, including skin texture, barrier support, and fine line care.

Key Benefits

• Overall skin regeneration and strengthening of the skin barrier across the entire face.

• Normalization of a compromised oil-water balance.

• Increased thickness of the dermal layer (resulting in a healthy, firm, and bouncy skin texture).

• Improvement of fine lines and a natural lifting effect.

Precautions and Characteristics

• Pain and Embossing: Because pure PN is a high-molecular-weight substance, pressure is generated when it enters the dermal layer, making the procedure quite painful. Additionally, due to its slow absorption rate, an 'embossing' effect—where the injection sites swell up in small bumps resembling mosquito bites—can last for about 3 to 5 days. If you have an important event coming up, it is highly recommended to receive the treatment at least a week in advance.

2. Rejuran HB Plus: Hydration & Pain Reduction

Treatment Features This is an upgraded version developed to drastically reduce the notorious 'pain' of the original Rejuran Healer. It combines the regenerative PN ingredient with moisture-drawing hyaluronic acid (HA) and 'lidocaine,' a local anesthetic, in a golden ratio.

Key Benefits

• Immediate hydration and a dewy, "glass skin" effect due to the addition of hyaluronic acid.

• Dual care offering both regeneration and moisturization.

• Over 50% reduction in pain compared to the original Rejuran, thanks to the lidocaine component.

Precautions and Characteristics

• Treatment Volume and Purpose: While the original Healer is typically administered in 2cc units per session, HB Plus is packaged in 1cc units. It is optimized for those who are highly sensitive to pain or who urgently need immediate relief from inner skin dryness alongside skin regeneration. However, the concentration of pure PN is slightly lower compared to the original.

3. Rejuran i: Dedicated Eye Booster

Treatment Features This is a product specifically dedicated to the eye area, with its viscosity and viscoelasticity lowered to be thin and gentle, tailored perfectly for the thinnest and most sensitive skin on our body. Because its consistency is light, it spreads evenly without clumping, even within thin skin tissues.

Key Benefits

• Improvement of fine lines under the eyes and crow's feet.

• Increased thickness and restored elasticity of the thinned skin around the eyes.

• Alleviation of dark circles (improving the visibility of underlying blood vessels as the skin tissue becomes healthier).

Precautions and Characteristics

• Targeting Thin Skin: Due to its low viscosity, it absorbs quickly, meaning the embossing effect is smaller and disappears much faster compared to the original Healer (usually within 1 to 2 days). It can also be effectively utilized for treating wrinkles on the thin and sensitive skin of the neck.

4. Rejuran S: Indented Scar Restoration

Treatment Features It boasts the highest viscosity and the heaviest consistency among the lineup. The 'S' stands for Scar, and true to its name, it is injected directly into deeply indented scarred areas to physically fill the empty space and help new tissue regenerate from within.

Key Benefits

• Improvement of indented acne scars and various types of depressed scars.

• Maximizes scar restoration synergy when combined with subcision (a procedure that severs the tangled fibrous bands underneath the scar).

• Intensive regeneration and volume formation in sunken areas.

Precautions and Characteristics

• Intensive Targeting on Localized Areas: Unlike the Healer, which is applied broadly across the entire face, this is intensively injected point-by-point specifically into the scarred areas. Because its viscosity is so high, a feeling of a foreign body or a raised, bumpy sensation at the treatment site may last a bit longer (about a week) compared to the other lineups.

5. Rejuran Treatment Results and Guidelines

Results and Timeline

• Most patients experience initial improvement after 1 to 2 weeks.

• Continuous improvement is seen over the following months as collagen production progresses.

• The standard treatment protocol is 3 to 4 sessions spaced 2 to 4 weeks apart, with maintenance treatments conducted every 6 to 12 months.

Cost in Korea

• The cost of a single Rejuran session in Seoul is generally $120 to $250

• In the US, similar PDRN treatments cost $300 to $500 or more.

Why Many Patients Choose QD Dermatology Clinic in Gangnam for Rejuran Treatments Rejuran was developed in Korea, and Korean dermatologists have been using it since its earliest products. The abundant clinical experience accumulated in Korea is unmatched. Additionally, by getting the treatment directly at its source, you can access genuine products at an affordable price.

[At-a-Glance Summary Table]

Product Name	Main Ingredients & Features	Solution Texture / Viscosity	Recommended Targets & Key Areas
Rejuran Healer	100% pure PN, the original Rejuran formula	Medium viscosity, standard texture	Overall facial skin rejuvenation, skin barrier support, anti-aging care
Rejuran HB Plus	PN + Hyaluronic Acid (HA) + local anesthetic	Medium viscosity, smoother texture	Suitable for patients sensitive to pain; helps improve skin hydration, skin repair, and a natural glowing effect
Rejuran I	Lightly refined pure PN	Very thin and lightweight texture	Designed for the delicate under-eye area, including fine lines and under-eye darkness
Rejuran S	Highly concentrated pure PN	High viscosity, dense texture	Targeted care for acne scars, depressed scars, and areas requiring intensive skin repair