Rejuran HBin Gangnam, Seoul
Rejuran HB is a polynucleotide (PN) skin booster that adds hyaluronic acid (HA) for immediate hydration, with lidocaine in the formula for a more comfortable injection. At QD Clinic in Gangnam, Seoul, South Korea, HB is often chosen for dry or dehydrated skin and by those who want hydration alongside skin repair. A session usually takes about 20–40 minutes including numbing. (Results vary by individual.)


Who it’s for
- Dry or dehydrated skin that needs hydration as well as repair
- Those who want an immediate plumping effect alongside skin quality
- People who prefer a more comfortable injection (lidocaine in the formula)
- Anyone new to Rejuran who wants a gentler first experience
Whether HB or another Rejuran formula suits you is confirmed during consultation.
How it works
Rejuran HB combines polynucleotides (PN) from salmon DNA with hyaluronic acid (HA), and its formula includes lidocaine. The PN supports the skin’s own repair, while the added HA provides immediate hydration and a plumping effect, and the lidocaine helps make the injections more comfortable. This blend is why HB is a frequent choice for dry or dehydrated skin and for those who prefer a gentler experience. “HB” refers to this hyaluronic-acid–blended formula.
THE MECHANISM, STEP BY STEP
01Polynucleotides plus hyaluronic acid
HB blends polynucleotides (PN) from salmon DNA with hyaluronic acid (HA), and its formula also includes lidocaine.
02Repair and immediate hydration
The PN supports the skin’s own repair, while the added HA provides immediate hydration and a plumping effect.
03A more comfortable injection
The lidocaine in the formula is intended to make the microinjections more comfortable, alongside the numbing cream applied first.
04Hydration early, quality over time
Hydration can be felt relatively early, while skin-quality change develops over a series of sessions. (Results vary by individual.)
Treatment areas
- Full face
- Hydration and skin quality across the face.
- Cheeks
- Dry, dull areas that need a hydration boost.
- Neck & décolletage
- Crepey, dehydrated skin on the neck and chest.
- Back of hands
- Thin, dehydrated skin on the hands, decided at consultation.
What the procedure is like
- 1Consultation and skin assessment
- 2Cleansing and numbing cream
- 3Microinjections across the treatment area
- 4Cooling, soothing and aftercare guidance
Time: A session takes about 20–40 minutes, including numbing time.
Recovery & aftercare
- Little downtime; small raised bumps at the injection sites may appear and usually settle within about 1–2 days.
- Temporary redness, mild swelling, tenderness or minor bruising may occur.
- Avoid makeup, saunas and intense exercise briefly, use sun protection, and follow the guidance we provide.
What to expect over time
A general guide to how the days and months after treatment usually unfold. Results vary by individual.
DAY 0 Treatment day
Numbing first, then microinjections. Small raised bumps at the injection sites are common, with mild redness or swelling; skin may feel hydrated.
DAY 1-2 Bumps settling
The small bumps usually settle within about 1–2 days. Minor bruising, if any, starts to fade.
WEEK 1 Hydration felt
Many people notice a hydrated, plumped feeling relatively early from the hyaluronic acid. This varies between people.
1-3 MONTHS Skin-quality change
Over the course and the following weeks, texture and elasticity may improve as the skin repairs. (Results vary by individual.)
AFTER THE COURSE Review & maintenance
Your doctor reviews the outcome and discusses maintenance timing based on your skin.
Sessions & results
A typical plan is about 3–4 sessions spaced roughly 2–4 weeks apart, with hydration felt early and skin quality developing gradually over the following weeks. Maintenance is considered after a period decided at consultation. (Results vary by individual.)
How it compares
These injectable boosters all support skin quality, but they add different things — so the right one depends on whether you want hydration, repair or collagen support.
| Comparison | Rejuran HB | Rejuran Healer | Juvelook Skin |
|---|---|---|---|
| Main agent | Polynucleotides + hyaluronic acid | Polynucleotides only | PDLLA microparticles + HA |
| Adds | Immediate hydration, comfort (lidocaine) | Repair support, no added HA | Gradual collagen support |
| Often chosen for | Dry or dehydrated skin | Overall skin quality | Texture, pores and glow |
| Sessions | Usually 3–4 | Usually 3–4 | Usually 2–3 |
| Downtime | Little; small bumps possible | Little; small bumps possible | Little; small papules possible |
Neither is “better” — they work differently and suit different goals. The right choice is decided after we assess your skin.
Safety & considerations
Possible reactions
- Small raised bumps at the injection sites, usually settling within about 1–2 days
- Temporary redness, mild swelling or a flushed feeling
- Tenderness in the treated area for a short time
- Occasionally minor bruising at injection points
When to take extra care
- Pregnancy or breastfeeding — let us know at consultation
- Active skin infection, inflammation or open lesions in the treatment area
- Known allergy or hypersensitivity, including to fish or salmon-derived products or to lidocaine
- A history of keloid or difficulty with wound healing
- Recent injectables or energy treatments in the area — tell your doctor so timing can be planned
Whether HB or another Rejuran formula suits your skin is confirmed during consultation. Effects vary by individual, and side effects may occur.
Your care at QD Clinic
Performed by a board-certified doctor
Your treatment is performed and medically reviewed by a board-certified doctor, not delegated unsupervised.
PN with hyaluronic acid
We offer the HB formula, which blends polynucleotides with hyaluronic acid, alongside the wider Rejuran range.
Care in your language
Consultation in English, with 中文 and 日本語 support arranged on request — including questions before you travel.
A short walk from Gangnam Station
Central Seoul location with guidance from the airport and nearby hotels, and hours shown in KST.
Frequently asked questions
HB refers to the hyaluronic-acid-blended formula. It combines polynucleotides from salmon DNA with hyaluronic acid, and the formula also contains lidocaine for comfort. The PN supports the skin's own repair, while the hyaluronic acid adds immediate hydration and a plumping effect.
Both contain hyaluronic acid and give a sense of hydration, but the main ingredient alongside it differs. Rejuran HB uses polynucleotides to support the skin's recovery environment, while Juvelook Skin uses fine PDLLA microparticles to prompt collagen production and work on texture, pores and fine lines. Which one we choose depends on whether dryness and skin recovery come first, or texture and pores, and that is decided at your examination.
The lidocaine in the formula is intended to reduce stinging during the injections, and a numbing cream is applied beforehand as well. Many people find it gentler than a formula without lidocaine, but how it feels still differs from person to person. Small raised bumps at the injection sites are common afterwards and usually settle within one to two days.
The added hyaluronic acid provides immediate hydration, which is why HB is often chosen for dry or dehydrated skin. Hydration is usually felt early, while the skin-quality changes from the PN develop gradually over the following weeks. We confirm at consultation whether your dryness calls for HB or another formula.
Most plans involve three to four sessions, each roughly two to four weeks apart. Hydration tends to be felt early, while skin quality develops gradually over the following weeks. After the course we review the change with you and decide when maintenance would make sense.
It is the same PN base with hyaluronic acid added. The hyaluronic acid brings moisture in straight away, and the PN then goes on supporting the skin's own recovery. That is why most people notice the hydrated, plumper feeling sooner after the session. It tends to be chosen by those who are troubled by dryness as well.
We first check whether assessment and any necessary follow-up fit your stay. Share your arrival, departure and important event dates before booking. For this treatment, the expected course is as follows. A typical plan is about 3–4 sessions spaced roughly 2–4 weeks apart, with hydration felt early and skin quality developing gradually over the following weeks. Maintenance is considered after a period decided at consultation. (Results vary by individual.) Temporary redness, mild swelling, tenderness or minor bruising may occur. Avoid makeup, saunas and intense exercise briefly, use sun protection, and follow the guidance we provide. Examination may lead to postponement or additional visits. Confirm contact arrangements after returning home and when in-person medical care may be needed. What the doctor checks first for this treatment: “Moisture and texture in dry, sensitive skin”.
Often considered together
Treatments that are sometimes planned alongside this one, decided at consultation.
+Ultrasound or RF lifting
Energy-based lifting addresses laxity and deeper support, which boosters do not target — sometimes planned together for skin quality plus firmness. Sequencing is decided by your doctor.
+Botulinum toxin
For dynamic lines from muscle movement (forehead, frown, crow’s feet), often planned alongside skin-quality treatments for a balanced result.
+Hyaluronic-acid filler
For areas where volume has softened, filler adds structure that a booster does not — planned together where appropriate at consultation.
For international patients
Consultation in English / 中文 / 日本語 · WhatsApp · WeChat · KakaoTalk · a 4-minute walk from Sinnonhyeon / Nonhyeon Station (hours in KST).
How many days should I stay?
Surgery and course-based treatments need a check-up. We tell you before you book whether that means staying longer or coming back another time.
For International Patients